Description
Mary & May Spicule Collagen PDRN Cream 15g is a concentrated Korean skincare treatment designed to support smoother texture, firmer-looking skin, visible pore care and a stronger moisture barrier. Its fragrance-free formula combines marine-derived micro-spicules with hydrolyzed collagen, CICA PDRN, panthenol, Ceramide NP, Sodium Hyaluronate and Allantoin.
The formula contains 1,000 ppm natural micro-spicules derived from hydrolyzed sponge. Mary & May describes these spicules as approximately 80–300 micrometres in size and smaller than the appearance of pores. One 15g tube is stated to contain approximately 90,000–100,000 microscopic spicules.
Micro-spicules create a temporary stimulating or prickling sensation when applied. This physical stimulation supports targeted care for rough texture, visible pores and fine lines. The sensation may remain noticeable for some time after application, especially when the treated area is touched.
The formula includes premium hydrolyzed marine collagen. Topical collagen primarily functions as a moisturizing and skin-conditioning ingredient, helping the surface of the skin appear smoother, softer and plumper. It should not be presented as permanently replacing the skin’s natural collagen.
CICA PDRN combines the soothing positioning of Centella-related skincare with Sodium DNA. It supports a calmer, healthier and recovered-looking complexion while complementing the product’s elasticity and barrier-care benefits. Cosmetic PDRN claims should remain focused on skin appearance rather than medical regeneration.
Panthenol is included at 2%. Also known as provitamin B5, panthenol helps replenish moisture, soothe discomfort and support the skin’s natural protective barrier. Its inclusion helps balance the stimulating sensation associated with micro-spicules.
Ceramide NP and cholesterol provide lipid-based barrier support. They help reinforce the skin’s moisture barrier and reduce the uncomfortable feeling associated with dryness. Hydrogenated lecithin, shea butter and macadamia seed oil further support softness and nourishment.
Sodium Hyaluronate and polyglutamic acid provide humectant care by helping attract and retain moisture at the skin’s surface. These ingredients support a hydrated, supple and plumper-looking finish.
Allantoin provides soothing and skin-conditioning benefits. Sodium Guaiazulene Sulfonate also complements the formula’s calming positioning, making the cream more balanced than a basic spicule-only treatment.
Niacinamide supports a brighter and more even-looking complexion while helping improve the appearance of excess surface oil and visible pores. Adenosine complements the formula with wrinkle-care and elasticity-focused benefits.
The formula also contains glycerin, Caprylic/Capric Triglyceride, shea butter and macadamia seed oil. These ingredients provide moisturizing and emollient care, helping reduce dryness and improve surface smoothness.
Mary & May states that the product has completed a skin irritation test. The brand also references testing associated with improvements in skin plumpness, barrier condition and elasticity. Individual results may vary according to skin condition, application frequency and routine compatibility.
Because the cream contains micro-spicules, it may cause a mild tingling or prickling sensation. This sensation is expected to be different from persistent burning, swelling or severe irritation. Sensitive skin should introduce the product gradually and use a small amount during the first applications.
The cream is most suitable for customers concerned with uneven texture, visible pores, dryness, reduced firmness and fine lines. It should not be applied to broken, inflamed, freshly exfoliated or recently treated skin.
Key Ingredients & Benefits
🪸 1,000 ppm Marine Micro-Spicules – Support targeted texture and visible pore care
💜 Hydrolyzed Collagen – Helps improve surface softness and a plumper appearance
🧬 CICA PDRN – Supports soothing care and healthier-looking skin
💧 2% Panthenol – Helps moisturize, soothe and reinforce the skin barrier
🧱 Ceramide NP & Cholesterol – Provide lipid-based moisture-barrier support
💦 Sodium Hyaluronate – Helps maintain surface hydration and suppleness
🌿 Allantoin – Supports a calmer and more comfortable skin feel
✨ Niacinamide – Supports brighter, more even-looking skin
🌙 Adenosine – Complements fine-line and elasticity-focused care
🚫 Fragrance-Free – Suitable for customers avoiding added artificial fragrance





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